B Kevin Park Selected Research

Sulfamethoxazole

6/2011	Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis.
6/2010	Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis.
1/2010	Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives.
4/2009	TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole.
12/2008	Nonenzymatic formation of a novel hydroxylated sulfamethoxazole derivative in human liver microsomes: implications for bioanalysis of sulfamethoxazole metabolites.
5/2007	Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.
1/2005	Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells.
7/2003	Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans.
5/2003	Mechanisms of drug hypersensitivity in HIV-infected patients: the role of the immune system.
2/2003	Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity.

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B Kevin Park Research Topics

Disease

43	Hypersensitivity (Allergy) 01/2021 - 09/2002
22	Chemical and Drug Induced Liver Injury 11/2020 - 10/2008
17	Necrosis 01/2020 - 12/2004
14	Drug-Related Side Effects and Adverse Reactions 01/2021 - 10/2003
10	Inflammation (Inflammations) 01/2020 - 09/2009
9	Neoplasms (Cancer) 04/2021 - 02/2004
7	Acute Liver Failure (Fulminant Hepatic Failure) 01/2020 - 11/2010
6	Mitochondrial Diseases (Mitochondrial Disease) 04/2021 - 01/2011
5	Drug Hypersensitivity (Drug Allergy) 01/2017 - 03/2011
5	Cystic Fibrosis (Mucoviscidosis) 06/2013 - 06/2010
4	Exanthema (Rash) 01/2021 - 06/2003
4	Cholestasis 12/2019 - 12/2013
4	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 09/2010
4	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2006
4	Stevens-Johnson Syndrome (Lyell's Syndrome) 08/2015 - 09/2006
4	Allergic Contact Dermatitis 03/2010 - 02/2007
3	Agranulocytosis (Granulocytopenia) 11/2020 - 10/2003
3	Liver Diseases (Liver Disease) 01/2017 - 01/2016
3	Acute Kidney Injury (Acute Renal Failure) 12/2015 - 12/2013
3	Chronic Renal Insufficiency 12/2015 - 11/2011
3	Hemorrhage 06/2014 - 07/2004
3	Malaria 09/2012 - 02/2004
3	Alzheimer Disease (Alzheimer's Disease) 05/2009 - 11/2007
2	Virus Diseases (Viral Diseases) 04/2021 - 01/2019
2	Neoplasm Metastasis (Metastasis) 02/2016 - 08/2011
2	Poisoning 10/2015 - 11/2011
2	Ischemia 11/2014 - 12/2013
2	Iatrogenic Disease 05/2013 - 02/2013
2	Pancreatic Neoplasms (Pancreatic Cancer) 04/2011 - 09/2010
2	Opportunistic Infections (Opportunistic Infection) 01/2010 - 04/2009
2	Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy) 05/2009 - 03/2008
2	Tinnitus 05/2009 - 03/2008
2	Carcinogenesis 04/2009 - 01/2005
2	Lipodystrophy 12/2004 - 10/2002
1	Immune System Diseases (Immune Disorders) 04/2021

Drug/Important Bio-Agent (IBA)

36	Pharmaceutical PreparationsIBA 01/2021 - 06/2003
16	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 10/2008
16	Proteins (Proteins, Gene)FDA Link 12/2017 - 01/2005
15	Biomarkers (Surrogate Marker)IBA 05/2018 - 11/2010
11	Sulfamethoxazole FDA LinkGeneric 06/2011 - 09/2002
10	Carbamazepine (Tegretol)FDA LinkGeneric 01/2021 - 07/2006
9	AntigensIBA 01/2018 - 09/2002
8	HMGB1 Protein (HMG1)IBA 01/2020 - 12/2009
8	abacavir (Ziagen)FDA Link 11/2015 - 05/2003
7	MicroRNAs (MicroRNA)IBA 01/2018 - 11/2011
7	Alanine Transaminase (SGPT)IBA 11/2016 - 11/2007
6	LactamsIBA 01/2018 - 06/2012
6	HLA-B Antigens (HLA-B)IBA 08/2015 - 06/2004
6	Keratin-18 (Keratin 18)IBA 03/2015 - 12/2009
5	HLA Antigens (Human Leukocyte Antigens)IBA 01/2021 - 09/2006
5	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 06/2010
5	Piperacillin FDA LinkGeneric 01/2018 - 07/2011
5	CaspasesIBA 03/2015 - 12/2009
4	HaptensIBA 01/2017 - 09/2011
4	HLA-B57 antigenIBA 08/2015 - 11/2012
4	4-phenylenediamine (p-phenylenediamine)FDA Link 08/2014 - 02/2007
3	Acetylcysteine (Siran)FDA LinkGeneric 01/2020 - 06/2014
3	Bile Acids and Salts (Bile Acids)IBA 12/2019 - 12/2013
3	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2012
3	brusatolIBA 01/2019 - 01/2015
3	Penicillins (Penicillin)FDA Link 12/2017 - 06/2009
3	Anticonvulsants (Antiepileptic Drugs)IBA 01/2017 - 04/2007
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2016 - 10/2002
3	AlbuminsIBA 09/2015 - 06/2013
3	SulfonamidesIBA 08/2014 - 02/2010
3	EnzymesIBA 03/2014 - 10/2003
3	Floxacillin (Flucloxacillin)IBA 02/2013 - 06/2009
3	Antimalarials (Antimalarial Agents)IBA 09/2012 - 11/2003
3	artemisinin (artemisinine)IBA 09/2012 - 04/2010
3	DNA (Deoxyribonucleic Acid)IBA 06/2012 - 05/2008
3	Tuberculin (PPD)IBA 03/2010 - 02/2007
2	HLA-A Antigens (HLA-A)IBA 01/2021 - 03/2011
2	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 11/2020 - 10/2016
2	Amoxicillin (Wymox)FDA LinkGeneric 11/2020 - 10/2016
2	Clozapine (Clozaril)FDA LinkGeneric 11/2020 - 10/2003
2	Protease Inhibitors (Protease Inhibitor)IBA 01/2019 - 12/2004
2	Therapeutic UsesIBA 11/2016 - 04/2013
2	EndotoxinsIBA 09/2015 - 12/2013
2	Peptides (Polypeptides)IBA 08/2015 - 06/2009
2	bardoxolone methylIBA 08/2014 - 08/2014
2	Diclofenac (SR 38)FDA LinkGeneric 08/2014 - 01/2007
2	Reverse Transcriptase InhibitorsIBA 04/2014 - 06/2004
2	NucleosidesIBA 04/2014 - 06/2004
2	Biological ProductsIBA 12/2013 - 04/2011
2	XenobioticsIBA 12/2013 - 04/2008
2	K-18 conjugate (K18)IBA 08/2013 - 12/2009
2	LipidsIBA 03/2013 - 12/2004
2	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2012 - 01/2011
2	Warfarin (Coumadin)FDA LinkGeneric 01/2012 - 07/2004
2	CarbonIBA 01/2011 - 05/2008
2	Indicators and Reagents (Reagents)IBA 11/2010 - 12/2009
2	GlycosidesIBA 05/2009 - 03/2008
2	Terpenes (Terpenoids)IBA 05/2009 - 03/2008
2	flavoneIBA 05/2009 - 03/2008
2	DiureticsIBA 09/2007 - 07/2004
1	pyrimidineIBA 04/2021
1	Leflunomide (Arava)FDA LinkGeneric 04/2021

Therapy/Procedure

9	Therapeutics 01/2021 - 04/2007
2	Drug Therapy (Chemotherapy) 02/2016 - 07/2006
2	Liver Transplantation 08/2015 - 11/2014